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BD OptiBuild? BUV496 Mouse Anti-Human HLA-A2 流式抗體



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品    牌:BD Biosciences

貨    號:741180

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商品名稱 規(guī)格 代理級別 價格 運費 供應商 購買
Hu HLA-A2 BUV496 BB7.2 50ug
交貨周期:28
50ug 經(jīng)銷
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北京賽泰克生物科技有限公司
庫存:99
BD OptiBuild? BUV496 Mouse Anti-Human HLA-A2 流式抗體
交貨周期:30
50 μg 經(jīng)銷
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廣州鋆泰生物科技有限公司
庫存:88
BD OptiBuild? BUV496 Mouse Anti-Human HLA-A2 流式抗體
交貨周期:30
50 μg 經(jīng)銷
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深圳市安迪康生物科技有限公司
庫存:1
Hu HLA-A2 BUV496 BB7.2 50ug
交貨周期:7
50ug 一級代理
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北京敏泰元科技有限公司
庫存:5
BD Pharmingen741180BUV496 Mouse Anti-Human HLA-A2(BB7.2)
交貨周期:部分現(xiàn)貨,期貨3-4周左右,優(yōu)質售后
50ug 經(jīng)銷
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上海優(yōu)寧維生物科技股份有限公司
庫存:999

  • 產(chǎn)品詳情

Alternative Name:HLA class I histocompatibility antigen A2 alpha chain; HLA-A2|Application:Flow cytometry (Qualified)|Brand:BD OptiBuild?|Concentration:0.2 mg/ml|Entrez Gene ID:3105|Immunogen:Papain-solubilized HLA-A2|Isotype:Mouse IgG2b, κ|Reactivity:Human (Tested in Development)|Regulatory Status:RUO|RRID:AB_2870747|Storage Buffer:Aqueous buffered solution containing ≤0.09% sodium azide.|描述: The monoclonal antibody BB7.2 specifically binds to the α subunit of the human leukocyte antigen-A2 (HLA-A2), a class I molecule of the major histocompatibility complex (MHC).??The MHC gene locus encodes a group of highly polymorphic, cell-surface proteins that play a broad role in the immune response to protein antigens. MHC molecules bind and present small antigenic protein fragments to antigen-specific receptors expressed by T cells (TCR). Human (human leukocyte antigen/HLA) MHC molecules are comprised of two major classes, MHC class I and class II.??Functionally, class I MHC molecules bind peptides derived from intracellular antigens (eg, viral and some bacterial antigens) which are specifically recognized by CD8+ T cells. Class II MHC molecules bind antigens derived from pathogens multiplying in intracellular vesicles and ingested extracellular bacteria, both of which are recognized by CD4+ T cells. TCR recognize processed peptides bound to the MHC as well as regions of the MHC molecule itself. CD4 and CD8 accessory molecules strengthen the formation of the TCR-MHC complex through their interaction with non-polymorphic regions of the MHC molecule. |商品通知:The production process underwent stringent testing and validation to assure that it generates a high-quality conjugate with consistent performance and specific binding activity. However, verification testing has not been performed on all conjugate lots.Researchers should determine the optimal concentration of this reagent for their individual applications.An isotype control should be used at the same concentration as the antibody of interest.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.For fluorochrome spectra and suitable instrument settings, please refer to our Multicolor Flow Cytometry web page BD Horizon Brilliant Ultraviolet 496 is covered by one or more of the following US patents: 8,110,673; 8,158,444; 8,227,187; 8,575,303; 8,354,239.BD Horizon Brilliant Stain Buffer is covered by one or more of the following US patents: 8,110,673; 8,158,444; 8,575,303; 8,354,239.Human donor specific background has been observed in relation to the presence of anti-polyethylene glycol (PEG) antibodies, developed as a result of certain vaccines containing PEG, including some COVID-19 vaccines. We recommend use of BD Horizon Brilliant? Stain Buffer in your experiments to help mitigate potential background. For U.S. patents that may apply, see bd.com/patents.|推薦的實驗流程: ?? BD? CompBeads can be used as surrogates to assess fluorescence spillover (compensation).??When fluorochrome conjugated antibodies are bound to BD? CompBeads, they have spectral properties very similar to cells.?? However, for some fluorochromes there can be small differences in spectral emissions compared to cells, resulting in spillover values that differ when compared to biological controls.??It is strongly recommended that when using a reagent for the first time, users compare the spillover on cells and BD? CompBeads to ensure that BD? CompBeads are appropriate for your specific cellular application. ?? For optimal and reproducible results, BD Horizon Brilliant Stain Buffer should be used anytime BD Horizon Brilliant dyes are used in a multicolor flow cytometry panel.??Fluorescent dye interactions may cause staining artifacts which may affect data interpretation.??The BD Horizon Brilliant Stain Buffer was designed to minimize these interactions. When BD Horizon Brilliant Stain Buffer is used in in the multicolor panel, it should also be used in the corresponding compensation controls for all dyes to achieve the most accurate compensation. For the most accurate compensation, compensation controls created with either cells or beads should be exposed to BD Horizon Brilliant Stain Buffer for the same length of time as the corresponding multicolor panel. More information can be found in the Technical Data Sheet of the BD Horizon Brilliant Stain Buffer (Cat. No. 563794/566349) or the BD Horizon Brilliant Stain Buffer Plus (Cat. No. 566385). Note:??When using high concentrations of antibody, background binding of this dye to erythroid cell subsets (mature erythrocytes and precursors) has been observed.??For researchers studying these cell populations, or in cases where light scatter gating does not adequately exclude these Cells from the analysis, this background may be an important factor to consider when selecting reagents for panel(s).

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